Posted On: 12/13/2007 2:57:27 PM
Hello,
I am new to this chat forum. My husband has been taking Lipitor for a couple of years. His numbers came down and then he started having leg pain. He stopped taking it and had blood drawn a few days ago and his numbers are up, including his liver enzymes. His Tryglicerides are down and HDL is up, but the LDL is up also. What can they give him to help if it damages his liver? Has anyone had any experience with this? I have been feeding only healthy foods, and added oat bran, flax seed, garlic capsules as well as Omega 3 and Artichoke extract. His mother had high cholesterol and was on Mevacor for years. Any suggestions??
I am new to this chat forum. My husband has been taking Lipitor for a couple of years. His numbers came down and then he started having leg pain. He stopped taking it and had blood drawn a few days ago and his numbers are up, including his liver enzymes. His Tryglicerides are down and HDL is up, but the LDL is up also. What can they give him to help if it damages his liver? Has anyone had any experience with this? I have been feeding only healthy foods, and added oat bran, flax seed, garlic capsules as well as Omega 3 and Artichoke extract. His mother had high cholesterol and was on Mevacor for years. Any suggestions??
1/4/2008 2:41:32 PM
Hi Janet,
Up to 20% can't take the statins due to side effects that include liver damage and damage to muscles. Sometimes these side effects can be serious and result in having to stop the medications.
There is a clinically proven natural alternative with Bios Life Complete. It's hard for a person to get the right amount of fiber in their diet, and Bios Life helps with this, plus works 4 ways to lower cholesterol without side effects. Several clinical studies have shown a real benefit, and it's listed in the PDR as well.
You might want to check out Bios Life at Womenshealthshoppe.com.
Up to 20% can't take the statins due to side effects that include liver damage and damage to muscles. Sometimes these side effects can be serious and result in having to stop the medications.
There is a clinically proven natural alternative with Bios Life Complete. It's hard for a person to get the right amount of fiber in their diet, and Bios Life helps with this, plus works 4 ways to lower cholesterol without side effects. Several clinical studies have shown a real benefit, and it's listed in the PDR as well.
You might want to check out Bios Life at Womenshealthshoppe.com.
2/13/2008 11:01:18 AM
Lipitor is the brand name for Atorvastatin a medicine prescribed to treat hypercholesteronemia which is believed to be one of the predisposing factors of CVD (Cardio Vascular Disease).
In animal models, LIPITOR lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing the number of hepatic LDL receptors on the cell-surface to enhance uptake and catabolism of LDL; LIPITOR also reduces LDL production and the number of LDL particles. LIPITOR reduces LDL-C in some patients with homozygous familial hypercholesterolemia (FH), a population that rarely responds to other lipid-lowering medication(s)
We all can agree, at least for the moment, in relation to the recent studies, that high concentration of LDL (bad cholesterol in our system greatly increases the risk of heart problems). Lipitor and Inegy (ezetimibe/simvastatin) are the two competing products that are out in the market these days that seem to capture the approval of most Cardiologist and Internist.
Lipitor is rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours. Extent of absorption increases in proportion to atorvastatin dose. The absolute bioavailability of atorvastatin (parent drug) is approximately 14% and the systemic availability of HMG-CoA reductase inhibitory activity is approximately 30%. The low systemic availability is attributed to presystemic clearance in gastrointestinal mucosa and/or hepatic first-pass metabolism. Although food decreases the rate and extent of drug absorption by approximately 25% and 9%, respectively, as assessed by Cmax and AUC, LDL-C reduction is similar whether atorvastatin is given with or without food. Plasma atorvastatin concentrations are lower (approximately 30% for Cmax and AUC) following evening drug administration compared with morning. However, LDL-C reduction is the same regardless of the time of day of drug administration.
These studies are conducted by research labs of the producers, and like most of the medications...there is always a contraindications and side effects that may arise, short or long term.
And through the fine prints, the disclosures are clearly spelled.
You have been doing a great deal of research and help to your husband. You mentioned some alternative remedies like flax seed and Omega 3.
They are so far found to have good effects on many users, no anecdotes on any side effects yet, so far.
Since you have taken that route, you might want to consider giving him Co-enzyme Q-10 as well. Or better yet, let him continue with his prescribed medicines and discuss with his doctors your plan of letting him try the Q-10 enzyme.
I hope that he's not taking any therapeutic blood thinners. Prophylactics like Aspirin is negligible but if he is on serious treatment like Counmadin and other stronger forms then he really need to discuss the plans with his Doctor. Because Co-enzyme Q-10 may reverse the effects of blood thinning purposes.
He may stop the other alternative source you have, so as not to confuse which one really works on him.
See, Lipitor may have been helping him but somehow it has a profound negative effects on his liver and other parts of his body.
We have to remember that everything that we take goes to a process called assimilation/absorption and there are certain enzymes necessary to aide the proper absorption of anything that we take orally.
Unfortunately as we grow older, our body is depleted of those necessary enzymes...so we we're advised to take fresh fruits and vegetables because process foods and those that are exposed to heat has no enzyme value, therefore, would only help us feel full/bloated but not enriched with nutrients.
The proper breakdown of food will continue but the distribution of the nutrients is altered.
The food that we take for breakfast is supposed to be converted into energy, the protein...for rebuilding and tissue repair called regeneration.
Our body cells goes into degenerative process every single day...if we cannot absorb the necessary nutritional components for tissue/cell regeneration, then we are guaranteed a breakdown (called disease process...some may even result to becoming carcinogenic).
The calories that are not use for energy...becomes an ornament on our side called love handles.
Which is a good business for Lipo suckers.
Yes we do ought to take fresh stuff (rich with enzymes) but at times, we fail to realize that the fruits and vegetables we buy from store shelves are no longer fresh. They have been sitting there for days or even weeks from time of harvest, transit and display.
Even those organically produce. Unless they have backyard of nursery, then and only then, they can guarantee freshness.
I wish we all have the resources and ability to have a nursery next to our kitchen.
So what are we to do given the situation?
Fortunately there are Scientific Technological Breakthroughs that are happening everyday...some are bad and some are good.
The one thing that will gain it's powerful entry into the wellness industry and alternative sources is not so much about newly identified vitamins, minerals and enzymes...but rather a technology that will help our body absorb those essential elements properly and effectively.
Omega 3, Q-10 enzymes, Micro/Macro Vitamins and Minerals are saturating the market...competing at shelves and screaming for us to pick them up.
They recommend mega dosing because of the breakdown in the absorption...once it enters into the stomach...it suffers the torments of Gastric Acid and if it is fat soluble...which most of them are, the chances is that fat attracts fat (solubility) they end up binding and clinging each other like sweethearts on Valentines Day.
They ain't going nowhere but stick around where they can be comfortable with their other buddies the HDL...now we have the condition term hypercholesterolenemia, pwe! ( I can't even say it.)
We don't need those mega doses...we already are stuffing foods that our body cannot convert properly 3 times a day and to some people maybe even more.
We need something that can properly break em' down and distribute to where it should go, rapidly and effectively.
There is a patented product from Germany that just gained it's entry here in United States.
This is the only product that focuses on carefully extracting enzymes from certified pesticide free, chemical free, raw materials of fresh fruits and vegetables package into a sealed and protected process to guarantee it's freshness, plus they are the only company that owns the patent for Nano Solve technology...(I can say this much easier than the hyperpwe!)
Nano meaning...the nutrients and enzymes we're preserved into tiny bits for easy delivery and absorption, Solve stands for water solubility...meaning...it doesn't stick to the fats...so it will never hang out with those pesky cholesterol that lurks like unwanted grease in our system.
So if you have a Nano (small enough to penetrate the semi-permeable membrane in our GI system), you are guaranteed that the process of breakdown and absorption of the food and convertion into energy called ATP (AdenosineTri-Phosphate) for effectively diffusing the nutrients (because of solvency) into the cell wall compartment rapidly (due to micellization process) which is sooo desperately needed by our body for tissue repair.
You can now expect that rejuvenation will follow inside and out.
That's an innovative concept. A breakthrough tech.
I wish there's a short and simple way to explain everything.
If you are intrigue and interested...please let me know. If you'll find that the product doesn't help then you have 90 days to return with a money back guarantee...as long as you return the empty cans.
I can present to you some testimonials from Olympian Ahtletes in Australia and Europe...but what good would that be if you yourself couldn't attest to the effects...this is not a look good feel good result.
These are dramatic and absolutely astounding results, that I wish never have to explain.
If I could only say...I don't know how! It just happens that my back injury for 18 from 16 years ago is now resolved...nah!
I can't do that because there is a sensible explanation than just merely placebo, miracles or will power.
Oregon State University did an elaborate study on Co-enzyme Q-10. Check the link in the bottom...unfortunately...they are still convince that Co-enzyme Q-10 is Fat Soluble...I have yet to present to them the Nano Solve and Micellized Technology.
But their study is a good reference to start.
http://lpi.oregonstate.edu/infocenter/othernuts/coq10/
I hope this helps and good luck...regards to your husband.
Fitline Champ, first in NY
In animal models, LIPITOR lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing the number of hepatic LDL receptors on the cell-surface to enhance uptake and catabolism of LDL; LIPITOR also reduces LDL production and the number of LDL particles. LIPITOR reduces LDL-C in some patients with homozygous familial hypercholesterolemia (FH), a population that rarely responds to other lipid-lowering medication(s)
We all can agree, at least for the moment, in relation to the recent studies, that high concentration of LDL (bad cholesterol in our system greatly increases the risk of heart problems). Lipitor and Inegy (ezetimibe/simvastatin) are the two competing products that are out in the market these days that seem to capture the approval of most Cardiologist and Internist.
Lipitor is rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours. Extent of absorption increases in proportion to atorvastatin dose. The absolute bioavailability of atorvastatin (parent drug) is approximately 14% and the systemic availability of HMG-CoA reductase inhibitory activity is approximately 30%. The low systemic availability is attributed to presystemic clearance in gastrointestinal mucosa and/or hepatic first-pass metabolism. Although food decreases the rate and extent of drug absorption by approximately 25% and 9%, respectively, as assessed by Cmax and AUC, LDL-C reduction is similar whether atorvastatin is given with or without food. Plasma atorvastatin concentrations are lower (approximately 30% for Cmax and AUC) following evening drug administration compared with morning. However, LDL-C reduction is the same regardless of the time of day of drug administration.
These studies are conducted by research labs of the producers, and like most of the medications...there is always a contraindications and side effects that may arise, short or long term.
And through the fine prints, the disclosures are clearly spelled.
You have been doing a great deal of research and help to your husband. You mentioned some alternative remedies like flax seed and Omega 3.
They are so far found to have good effects on many users, no anecdotes on any side effects yet, so far.
Since you have taken that route, you might want to consider giving him Co-enzyme Q-10 as well. Or better yet, let him continue with his prescribed medicines and discuss with his doctors your plan of letting him try the Q-10 enzyme.
I hope that he's not taking any therapeutic blood thinners. Prophylactics like Aspirin is negligible but if he is on serious treatment like Counmadin and other stronger forms then he really need to discuss the plans with his Doctor. Because Co-enzyme Q-10 may reverse the effects of blood thinning purposes.
He may stop the other alternative source you have, so as not to confuse which one really works on him.
See, Lipitor may have been helping him but somehow it has a profound negative effects on his liver and other parts of his body.
We have to remember that everything that we take goes to a process called assimilation/absorption and there are certain enzymes necessary to aide the proper absorption of anything that we take orally.
Unfortunately as we grow older, our body is depleted of those necessary enzymes...so we we're advised to take fresh fruits and vegetables because process foods and those that are exposed to heat has no enzyme value, therefore, would only help us feel full/bloated but not enriched with nutrients.
The proper breakdown of food will continue but the distribution of the nutrients is altered.
The food that we take for breakfast is supposed to be converted into energy, the protein...for rebuilding and tissue repair called regeneration.
Our body cells goes into degenerative process every single day...if we cannot absorb the necessary nutritional components for tissue/cell regeneration, then we are guaranteed a breakdown (called disease process...some may even result to becoming carcinogenic).
The calories that are not use for energy...becomes an ornament on our side called love handles.
Which is a good business for Lipo suckers.
Yes we do ought to take fresh stuff (rich with enzymes) but at times, we fail to realize that the fruits and vegetables we buy from store shelves are no longer fresh. They have been sitting there for days or even weeks from time of harvest, transit and display.
Even those organically produce. Unless they have backyard of nursery, then and only then, they can guarantee freshness.
I wish we all have the resources and ability to have a nursery next to our kitchen.
So what are we to do given the situation?
Fortunately there are Scientific Technological Breakthroughs that are happening everyday...some are bad and some are good.
The one thing that will gain it's powerful entry into the wellness industry and alternative sources is not so much about newly identified vitamins, minerals and enzymes...but rather a technology that will help our body absorb those essential elements properly and effectively.
Omega 3, Q-10 enzymes, Micro/Macro Vitamins and Minerals are saturating the market...competing at shelves and screaming for us to pick them up.
They recommend mega dosing because of the breakdown in the absorption...once it enters into the stomach...it suffers the torments of Gastric Acid and if it is fat soluble...which most of them are, the chances is that fat attracts fat (solubility) they end up binding and clinging each other like sweethearts on Valentines Day.
They ain't going nowhere but stick around where they can be comfortable with their other buddies the HDL...now we have the condition term hypercholesterolenemia, pwe! ( I can't even say it.)
We don't need those mega doses...we already are stuffing foods that our body cannot convert properly 3 times a day and to some people maybe even more.
We need something that can properly break em' down and distribute to where it should go, rapidly and effectively.
There is a patented product from Germany that just gained it's entry here in United States.
This is the only product that focuses on carefully extracting enzymes from certified pesticide free, chemical free, raw materials of fresh fruits and vegetables package into a sealed and protected process to guarantee it's freshness, plus they are the only company that owns the patent for Nano Solve technology...(I can say this much easier than the hyperpwe!)
Nano meaning...the nutrients and enzymes we're preserved into tiny bits for easy delivery and absorption, Solve stands for water solubility...meaning...it doesn't stick to the fats...so it will never hang out with those pesky cholesterol that lurks like unwanted grease in our system.
So if you have a Nano (small enough to penetrate the semi-permeable membrane in our GI system), you are guaranteed that the process of breakdown and absorption of the food and convertion into energy called ATP (AdenosineTri-Phosphate) for effectively diffusing the nutrients (because of solvency) into the cell wall compartment rapidly (due to micellization process) which is sooo desperately needed by our body for tissue repair.
You can now expect that rejuvenation will follow inside and out.
That's an innovative concept. A breakthrough tech.
I wish there's a short and simple way to explain everything.
If you are intrigue and interested...please let me know. If you'll find that the product doesn't help then you have 90 days to return with a money back guarantee...as long as you return the empty cans.
I can present to you some testimonials from Olympian Ahtletes in Australia and Europe...but what good would that be if you yourself couldn't attest to the effects...this is not a look good feel good result.
These are dramatic and absolutely astounding results, that I wish never have to explain.
If I could only say...I don't know how! It just happens that my back injury for 18 from 16 years ago is now resolved...nah!
I can't do that because there is a sensible explanation than just merely placebo, miracles or will power.
Oregon State University did an elaborate study on Co-enzyme Q-10. Check the link in the bottom...unfortunately...they are still convince that Co-enzyme Q-10 is Fat Soluble...I have yet to present to them the Nano Solve and Micellized Technology.
But their study is a good reference to start.
http://lpi.oregonstate.edu/infocenter/othernuts/coq10/
I hope this helps and good luck...regards to your husband.
Fitline Champ, first in NY
7/17/2008 2:48:39 PM
Hi Janet,
One thing I learned from a Dr is... there is no safe drug. Why take drug to get the same effect in a natural food substance? Have you heard of the fruit called the mangosteen? Probably not as it is primarily grown in Southeast Asia. It has been used in traditional medicine for over thousands of years. And Xanthones, which are found richly in the pericarp (or rind) of the fruit is the subject of extensive positive research. I know of a Dr who actually replaces drug with the mangosteen juice! In his article that I read, he says that "mangosteen equals or outperforms the following prescriptions and over-the-counter drugs", and included in his list are Lipitor, Zocor, Pravacol and other lipid-lowering agents. He advocates the use of the mangosteen juice as it is 100% natural, xanthone-rich (powerful anti-oxidants), and no adverse side-effect. Me and my husband are drinking the juice too because it has anti-tumor benefits as well (I had a portion of my colon removed 7 yrs ago because of tumor growth). Here's a link that you may find helpful to understand more of this miracle fruit. By the way, this fruit juice is not found in health stores. Me and my husband got it from a distributor. Let me know if you're interested. You and your husband has nothing to lose...
One thing I learned from a Dr is... there is no safe drug. Why take drug to get the same effect in a natural food substance? Have you heard of the fruit called the mangosteen? Probably not as it is primarily grown in Southeast Asia. It has been used in traditional medicine for over thousands of years. And Xanthones, which are found richly in the pericarp (or rind) of the fruit is the subject of extensive positive research. I know of a Dr who actually replaces drug with the mangosteen juice! In his article that I read, he says that "mangosteen equals or outperforms the following prescriptions and over-the-counter drugs", and included in his list are Lipitor, Zocor, Pravacol and other lipid-lowering agents. He advocates the use of the mangosteen juice as it is 100% natural, xanthone-rich (powerful anti-oxidants), and no adverse side-effect. Me and my husband are drinking the juice too because it has anti-tumor benefits as well (I had a portion of my colon removed 7 yrs ago because of tumor growth). Here's a link that you may find helpful to understand more of this miracle fruit. By the way, this fruit juice is not found in health stores. Me and my husband got it from a distributor. Let me know if you're interested. You and your husband has nothing to lose...
