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Hormones Used to Reduce Breast Cancer Risk and Menopause Symptoms

Hormones Used to Reduce Breast Cancer Risk and Menopause Symptoms

According to new research at Yale, a combination of estrogen and a selective estrogen receptor modulator (SERM) can lower the risk of breast cancer and reduce the symptoms of menopause. Women who have symptoms of menopause but have not had a hysterectomy are currently treated with a combination of estrogen and progestin therapy, but this increases the risk of breast cancer because of the progestin.

By using a SERM instead of progestin, the growth of breast and endometrial cells that can lead to cancer is blocked, so women can get the benefits of estrogen without the risk of progestin. The key is to use the right combination of estrogen and various SERMs that was identified in the study.

These lab results are now being tested in larger clinical trials.

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